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Cdk5 Antibody

Catalog # Availability Size / Price Inquiry
AMM02591G 100 μl / $545

Cdk5 Antibody

Brand

Leading Biology

Catalog Number

AMM02591G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cdk5 Antibody.

Molecular Weight

28 KDa

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Target

Purified rat Cdk5.

Clone

1H3

Isotype

IgG1

GeneID

UniProt ID

Summary

The neuronal protein kinase, Cdk5 has been implicated in a vast array of normal neuronal functions including regulation of neurotransmitter synthesis (Kansy J et al., 2004), the presynaptic vesicle cycle (Nguyen, C. & Bibb, JA 2003), neurotransmitter receptor trafficking and dopamine neurotransmission (Bibb, JA et al. 1999). At the same time Cdk5 has been implicated in a plethora of neurological and neuropsychiatric disorders including Alzheimer’s, Parkinson’s, Huntington’s, epilepsy, schizophrenia, and drug addiction. Detection of Cdk5 in normal samples as well as tissue undergoing neurodegeneration may advance studies in these areas. Moreover, this antibody may allow more accurate postmortem evaluations of Cdk5 protein expression, and thus serve as a valuable new reagent for neuropathology.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, IF, WB, FC

Dilution

IHC~~1:500 IF~~1:500 FC~~1:500 WB~~ 1:1000

Images

Immunohistochemical analysis of paraffin-embedded R. brain section using Cdk5 Antibody ( AMM02591G). AMM02591G was diluted at 1:500 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded H. brain section using Cdk5 Antibody ( AMM02591G). AMM02591G was diluted at 1:500 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded M. brain section using Cdk5 Antibody ( AMM02591G). AMM02591G was diluted at 1:500 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Specification

Quantity

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