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PAX4 Antibody

Catalog # Availability Size / Price Inquiry
AMM02814G 100 μl / $495

PAX4 Antibody

Brand

Leading Biology

Catalog Number

AMM02814G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAX4 Antibody.

Molecular Weight

38kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Mouse

Species Reactivity

Human

Clone

3C12

Isotype

IgG1

GeneID

UniProt ID

Function

Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

E~~1/10000 WB~~1/500 - 1/2000

Images

Red: Control Antigen (100ng);Purple: Antigen (10ng);Green: Antigen (50ng);Blue: Antigen (100ng);

Figure 1: Western blot analysis using PAX4 mAb against HEK293 (1) and PAX4(AA: 105-232)-hIgGFc transfected HEK293 (2) cell lysate.

Specification

Quantity

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