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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > RIP1 / RALBP1 Antibody (clone OTI1H9)

RIP1 / RALBP1 Antibody (clone OTI1H9)

Catalog # Availability Size / Price Inquiry
AMM02311G 50 μl / $495

RIP1 / RALBP1 Antibody (clone OTI1H9)

Brand

Leading Biology

Catalog Number

AMM02311G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RIP1 / RALBP1 Antibody (clone OTI1H9).

Molecular Weight

76063 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Peripheral membrane protein

Host

Mouse

Species Reactivity

Human

Target

Human RALBP1

Clone

OTI1H9

Isotype

IgG1

Symbol

RLIP1, RLIP76

GeneID

UniProt ID

Function

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Summary

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, Flo

Dilution

Flo (1:100), IHC-P (10 μg/ml), WB (1:2000),

Images

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RALBP1...

HEK293T cells transfected with either pCMV6-ENTRY RALBP1 (Red) or empty vector control plasmid...

Specification

Quantity

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