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EMA / MUC1 Antibody (clone CM1)

Catalog # Availability Size / Price Inquiry
AMM02045G Discontinued 50 μg / $495

EMA / MUC1 Antibody (clone CM1)

Brand

Leading Biology

Catalog Number

AMM02045G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EMA / MUC1 Antibody (clone CM1).

Molecular Weight

122kDa

Cellular Localization

Antigen Cellular Localization: Apical cell membrane; Single- pass type I membrane protein. Note=Exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. After endocytosis, internalized and recycled to the cell membrane. Located to microvilli and to the tips of long filopodial protusions Isoform Y: Secreted. Mucin-1 subunit beta: Cell membrane. Cytoplasm. Nucleus. Note=On EGF and PDGFRB stimulation, transported to the nucleus through interaction with CTNNB1, a process which is stimulated by phosphorylation. On HRG stimulation, colocalizes with JUP/gamma-catenin at the nucleus

Host

Mouse

Species Reactivity

Human

Target

VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids or as a result of chemical treatment of human milk MUC1. These MAbs do not recognize natural MUC1 protein isolated from human ...

Clone

CM1

Symbol

PUM

GeneID

UniProt ID

Function

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.

Summary

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IF, IHC-Fr

Dilution

IHC-Fr, IHC-P (10 μg/ml),

Images

Anti-MUC1 antibody IHC of human breast.

Anti-MUC1 antibody IHC of human uterus.

Specification

Quantity

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