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CD40 Antibody (clone LOB7/6)

Catalog # Availability Size / Price Inquiry
AMM01768G 50 μg / $495

CD40 Antibody (clone LOB7/6)

Brand

Leading Biology

Catalog Number

AMM01768G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD40 Antibody (clone LOB7/6).

Molecular Weight

31kDa

Cellular Localization

Antigen Cellular Localization: Isoform I: Cell membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human, Dog

Target

Recognizes human CD40 cell surface antigen, a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centers and is vital in T cell-B cell interactions.

Clone

LOB7/6

Symbol

TNFRSF5

GeneID

UniProt ID

Function

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Summary

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IP, IHC-Fr, Flo

Dilution

Flo (20 μg/ml), IHC-Fr (1-10 μg/ml), IHC-P (10 μg/ml)

Images

Anti-CD40 antibody IHC of human spleen.

Specification

Quantity

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