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CD59 Antibody (clone MEM-43)

Catalog # Availability Size / Price Inquiry
AMM01753G 50 μg / $495

CD59 Antibody (clone MEM-43)

Brand

Leading Biology

Catalog Number

AMM01753G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD59 Antibody (clone MEM-43).

Molecular Weight

14kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues

Host

Mouse

Species Reactivity

Human

Clone

MEM-43

Symbol

MIC11, MIN1, MIN2, MIN3, MSK21

GeneID

UniProt ID

Function

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Summary

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E, IP, IHC-Fr, Flo

Dilution

IHC-P (5 μg/ml)

Images

Anti-CD59 antibody IHC of human skin, sweat glands.

Specification

Quantity

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