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TAB2 Antibody

Catalog # Availability Size / Price Inquiry
AMM02803G 100 μl / $495

TAB2 Antibody

Brand

Leading Biology

Catalog Number

AMM02803G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TAB2 Antibody.

Molecular Weight

80kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Peripheral membrane protein Cytoplasm, cytosol. Note=Following IL1 stimulation, translocation occurs from the membrane to cytosol

Host

Mouse

Species Reactivity

Human

Clone

3B5

Isotype

IgG1

Symbol

KIAA0733, MAP3K7IP2

GeneID

UniProt ID

Function

Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'- linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1/500 - 1/2000 FC~~1/200 - 1/400

Images

Figure 1: Western blot analysis using TAB2 mAb against HEK293 (1) and TAB2(AA: 1-300)-hIgGFc transfected HEK293 (2) cell lysate.

Figure 2: Flow cytometric analysis of HL-60 cells using TAB2 mouse mAb (green) and negative control (purple).

Specification

Quantity

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