> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > FMR1 AntibodyBrand |
Leading Biology | Catalog Number |
AMM02709G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FMR1 Antibody.
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Molecular Weight |
71kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleolus.
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
4G9
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, ICC, E
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Dilution |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
ICC~~1:200~~1000
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Images |
Figure 1: Western blot analysis using FMR1 mouse mAb against Jurkat (1) and K562 (2) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 mouse mAb.
Figure 3: Immunofluorescence analysis of NIH/3T3 cells using FMR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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