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MDM4 Antibody

AMM02677G Product Datasheet Protocol

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AMM02677G		100 μl / $495

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Leading Biology Inc.

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MDM4 Antibody

Brand	Leading Biology	Catalog Number	AMM02677G
Product Type	Monoclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MDM4 Antibody.
Molecular Weight	55kDa
Cellular Localization	Antigen Cellular Localization: Nucleus.
Host	Mouse
Species Reactivity	Human
Clone	2D10F4
Isotype	IgG1
Symbol	MDMX
GeneID	4194
UniProt ID	O15151
Function	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC, ICC, E
Dilution	WB~~1/500 - 1/2000 IHC~~1/500 - 1/2000 IF~~1/200 - 1/1000
Images	Figure 1: Western blot analysis using MDM4 mouse mAb against Hela (1), A549 (2) and A431 (3) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebra (left) and lung carcinoma (right) tissues, showing nuclear localization with DAB staining using MDM4 mouse mAb. Figure 3: Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using MDM4 mouse mAb
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