> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > HLA-DPA1 Antibody (monoclonal) (M03)Brand |
Leading Biology | Catalog Number |
AMM03624G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HLA-DPA1 Antibody (monoclonal) (M03).
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Molecular Weight |
29381 Da
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Host |
mouse
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Species Reactivity |
Human
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Target |
HLA-DPA1 (AAH09956, 1 a.a. ~ 260 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Clone |
1E4
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Isotype |
IgG2a Kappa
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GeneID |
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UniProt ID |
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Summary |
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:500~1000
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Images |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (54.34 KDa) .
Western Blot analysis of HLA-DPA1 expression in transfected 293T cell line by HLA-DPA1 monoclonal antibody (M03), clone 1E3.Lane 1: HLA-DPA1 transfected lysate(29.3 KDa).Lane 2: Non-transfected lysate.
Detection limit for recombinant GST tagged HLA-DPA1 is approximately 3ng/ml as a capture antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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