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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > GP1BA Antibody (monoclonal) (M02)

GP1BA Antibody (monoclonal) (M02)

Catalog # Availability Size / Price Inquiry
AMM03588G 100 μg / $495

GP1BA Antibody (monoclonal) (M02)

Brand

Leading Biology

Catalog Number

AMM03588G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GP1BA Antibody (monoclonal) (M02).

Molecular Weight

71540 Da

Host

mouse

Species Reactivity

Human

Target

GP1BA (AAH27955, 19 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

1C6

Isotype

IgG2a Kappa

GeneID

UniProt ID

Summary

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IP, E

Dilution

WB~~1:500~1000

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .

Immunoprecipitation of GP1BA transfected lysate using anti-GP1BA monoclonal antibody and Protein A Magnetic Bead (<a href="products_detail.asp?Catalog_id=U0007">U0007</a>), and immunoblotted with GP1BA MaxPab rabbit polyclonal antibody.

Detection limit for recombinant GST tagged GP1BA is approximately 0.03ng/ml as a capture antibody.

Specification

Quantity

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