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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > EIF4G2 Antibody (monoclonal) (M01)

EIF4G2 Antibody (monoclonal) (M01)

Catalog # Availability Size / Price Inquiry
AMM03487G 100 μg / $495

EIF4G2 Antibody (monoclonal) (M01)

Brand

Leading Biology

Catalog Number

AMM03487G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF4G2 Antibody (monoclonal) (M01).

Molecular Weight

102362 Da

Host

mouse

Species Reactivity

Human, Rat

Target

EIF4G2 (NP_001409, 811 a.a. ~ 889 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

3B5

Isotype

IgG1 Kappa

GeneID

UniProt ID

Summary

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Dilution

WB~~1:500~1000

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.43 KDa) .

EIF4G2 monoclonal antibody (M01), clone 3B5. Western Blot analysis of EIF4G2 expression in PC-12 ( AMM03487G )

EIF4G2 monoclonal antibody (M01), clone 3B5 Western Blot analysis of EIF4G2 expression in Hela S3 NE ( AMM03487G )

Specification

Quantity

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