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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CDKN2D Antibody (monoclonal) (M08)

CDKN2D Antibody (monoclonal) (M08)

Catalog # Availability Size / Price Inquiry
AMM03374G 100 μg / $495

CDKN2D Antibody (monoclonal) (M08)

Brand

Leading Biology

Catalog Number

AMM03374G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN2D Antibody (monoclonal) (M08).

Molecular Weight

17700 Da

Host

mouse

Species Reactivity

Human

Target

CDKN2D (AAH01822, 1 a.a. ~ 166 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2E11

Isotype

IgG2b Kappa

GeneID

UniProt ID

Summary

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IP, E

Dilution

WB~~1:500~1000

Images

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44 KDa) .

Western Blot analysis of CDKN2D expression in transfected 293T cell line by CDKN2D monoclonal antibody (M08), clone 2E10.Lane 1: CDKN2D transfected lysate(17.7 KDa).Lane 2: Non-transfected lysate.

Immunoprecipitation of CDKN2D transfected lysate using anti-CDKN2D monoclonal antibody and Protein A Magnetic Bead (<a href="products_detail.asp?Catalog_id=U0007">U0007</a>), and immunoblotted with CDKN2D MaxPab rabbit polyclonal antibody.

Specification

Quantity

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