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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody - Without BSA and Azide

AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody - Without BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM00778G 100 μg / $495

AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody - Without BSA and Azide

Brand

Leading Biology

Catalog Number

AMM00778G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody - Without BSA and Azide.

Molecular Weight

~90kDa

Host

Mouse

Species Reactivity

Human

Clone

AMPD3/901

Isotype

Mouse / IgG2b, kappa

GeneID

UniProt ID

Function

AMP deaminase plays a critical role in energy metabolism.

Summary

It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-F, IF, FC, ICC

Images

Formalin-fixed, paraffin-embedded human Tonsil stained with AMPD3 Monoclonal Antibody (AMPD3/901)

Formalin-fixed, paraffin-embedded human Placenta stained with AMPD3 Monoclonal Antibody (AMPD3/901)

Specification

Quantity

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