> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Cytokeratin 8/18 Antibody - Without BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00503G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 8/18 Antibody - Without BSA and Azide.
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Molecular Weight |
52.5kDa (CK8); 45kDa (CK18)
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
K8.8 + DC10
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Isotype |
Mouse / IgG's
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Symbol |
CYK8
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GeneID |
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UniProt ID |
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Function |
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
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Summary |
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.?Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, FC
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Images |
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Specification |
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Quantity |
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| 5 | Leading Biology | AMM00172G | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
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| 6 | Leading Biology | AMM05750G | CEBPA Antibody | 100 μl | Monoclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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