> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Actin, Smooth Muscle (Leiomyosarcoma Marker) Antibody - Without BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00389G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Actin, Smooth Muscle (Leiomyosarcoma Marker) Antibody - Without BSA and Azide.
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Molecular Weight |
42kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Mouse
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Species Reactivity |
Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Goat, Baboon, Cow, Sheep, Guinea Pig, Dog, Cat
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Clone |
SPM332
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Isotype |
Mouse / IgG2a, kappa
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Symbol |
ACTSA, ACTVS
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GeneID |
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UniProt ID |
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Function |
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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Summary |
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, IF, FC
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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