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Hsp90 Antibody

Catalog # Availability Size / Price Inquiry
AMM02455G 100 μl / $495

Hsp90 Antibody

Brand

Leading Biology

Catalog Number

AMM02455G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Hsp90 Antibody.

Molecular Weight

84660 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Melanosome. Cell membrane. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Target

This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 150-400 amino acids from human.

Clone

803CT9.1.2

Isotype

IgG1,λ

Symbol

HSP90A, HSPC1, HSPCA

GeneID

UniProt ID

Function

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Summary

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of lysates from rat L6, mouse NIH/3T3, T47D, A2058, HepG2, K562, Hela cell line (from left to right), using Hsp90 Antibody(AMM02455G). AMM02455G was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.

Specification

Quantity

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