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VEGFC Antibody

Catalog # Availability Size / Price Inquiry
AMM02352G 100 μl / $495

VEGFC Antibody

Brand

Leading Biology

Catalog Number

AMM02352G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VEGFC Antibody.

Molecular Weight

46883 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Target

This VEGFC monoclonal antibody is generated from mouse immunized with VEGFC recombinant protein.

Clone

197CT7.3.4

Isotype

IgG1,K

GeneID

UniProt ID

Function

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Summary

The protein encoded by this gene is a member of theplatelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family, is active in angiogenesis and endothelial cellgrowth, and can also affect the permeability of blood vessels.This secreted protein undergoes a complex proteolytic maturation,generating multiple processed forms which bind and activate VEGFR-3receptors. Only the fully processed form can bind and activateVEGFR-2 receptors. This protein is structurally and functionallysimilar to vascular endothelial growth factor D. [provided byRefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

All lanes : Anti-VEGFC at 1:2000 dilution Lane 1: CCRF-CEM whole cell lysate Lane 2: 293 whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: mouse heart lysate Lane 5: rat heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of lysates from 293, CEM cell line and mouse heart, rat heart tissue lysates (from left to right), using VEGFC Antibody( AMM02352G). AMM02352G was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.

Specification

Quantity

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