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CAPN6 Antibody

Catalog # Availability Size / Price Inquiry
AMM02517G 100 μl / $495

CAPN6 Antibody

Brand

Leading Biology

Catalog Number

AMM02517G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAPN6 Antibody.

Molecular Weight

74576 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle

Host

Mouse

Species Reactivity

Mouse

Target

This CAPN6 antibody is generated from a mouse immunized with a recombinant protein of human CAPN6.

Clone

1395CT446.22.5

Isotype

IgG1

Symbol

CALPM, CANPX

GeneID

UniProt ID

Function

Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity).

Summary

Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

FC, WB, E

Dilution

FC~~1:25 WB~~1:1000

Images

Flow cytometric analysis of A549 cells using CAPN6 Antibody(green, AMM02517G) compared to an isotype control of mouse IgG1(blue). was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Western blot analysis of lysate from human placenta tissue lysate, using CAPN6 Antibody(AMM02517G). AMM02517G was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20μg.

Specification

Quantity

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