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VWF Antibody

Catalog # Availability Size / Price Inquiry
AMM02506G 100 μl / $495

VWF Antibody

Brand

Leading Biology

Catalog Number

AMM02506G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VWF Antibody.

Molecular Weight

309265 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules

Host

Mouse

Species Reactivity

Human

Target

This antibody is generated from a mouse immunized with .VWF recombinant protein.

Clone

907CT12.1.9

Isotype

IgG1

Symbol

F8VWF

GeneID

UniProt ID

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Summary

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

FC~~1:100 IHC-P~~1:25 WB~~1:1000

Images

Flow cytometric analysis of K562 cells using VWF(green, AMM02506G) compared to an isotype control of mouse IgG1(blue). AP20600c was diluted at 1:100 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded H. kidney section using VWF( AMM02506G). AMM02506G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Western blot analysis of lysate from VWF protein, using VWF Antibody(AMM02506G). AMM02506G was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35μg.

Specification

Quantity

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