> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > IL2 Antibody (Center) (Ascites)Brand |
Leading Biology | Catalog Number |
AMM02432G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL2 Antibody (Center) (Ascites).
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Molecular Weight |
17628 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
50-77 aa
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Target |
This IL2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the Central region of human IL2.
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Clone |
627CT14.8.1
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.
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Summary |
The protein encoded by this gene is a secreted cytokinethat is important for the proliferation of T and B lymphocytes. Thereceptor of this cytokine is a heterotrimeric protein complex whosegamma chain is also shared by interleukin 4 (IL4) and interleukin 7(IL7). The expression of this gene in mature thymocytes ismonoallelic, which represents an unusual regulatory mode forcontrolling the precise expression of a single gene. The targeteddisruption of a similar gene in mice leads to ulcerativecolitis-like disease, which suggests an essential role of this genein the immune response to antigenic stimuli.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~1600
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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