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HKLK3 Antibody (C234)

Catalog # Availability Size / Price Inquiry
AMM02424G 100 μl / $495

HKLK3 Antibody (C234)

Brand

Leading Biology

Catalog Number

AMM02424G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HKLK3 Antibody (C234).

Molecular Weight

28741 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Mouse

Species Reactivity

Human

Immunogen

220-250 aa

Target

This HKLK3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from human HKLK3.

Clone

551CT16.3.5

Isotype

IgM

Symbol

APS

GeneID

UniProt ID

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Summary

Kallikreins are a subgroup of serine proteases havingdiverse physiological functions. Growing evidence suggests thatmany kallikreins are implicated in carcinogenesis and some havepotential as novel cancer and other disease biomarkers. This geneis one of the fifteen kallikrein subfamily members located in acluster on chromosome 19. Its protein product is a protease presentin seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of thehigh molecular mass seminal vesicle protein. Serum level of thisprotein, called PSA in the clinical setting, is useful in thediagnosis and monitoring of prostatic carcinoma. Alternate splicingof this gene generates several transcript variants encodingdifferent isoforms.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100

Images

HKLK3 Antibody (C234)(Cat. AMM02424G) western blot analysis in MDA-MB231 cell line lysates (35μg/lane).This demonstrates the HKLK3 antibody detected the HKLK3 protein (arrow).

Specification

Quantity

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