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MMP9 Antibody

Catalog # Availability Size / Price Inquiry
AMM02382G 100 μl / $495

MMP9 Antibody

Brand

Leading Biology

Catalog Number

AMM02382G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMP9 Antibody.

Molecular Weight

78458 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Mouse

Species Reactivity

Human

Target

Purified His-tagged MMP9 protein(Fragment) was used to produced this monoclonal antibody.

Clone

331CT17.4.4

Isotype

IgM

Symbol

CLG4B

GeneID

UniProt ID

Function

May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.

Summary

Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The enzyme encoded by this genedegrades type IV and V collagens. Studies in rhesus monkeys suggestthat the enzyme is involved in IL-8-induced mobilization ofhematopoietic progenitor cells from bone marrow, and murine studiessuggest a role in tumor-associated tissue remodeling. [provided byRefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100~250

Images

All lanes : Anti-MMP9 Antibody at 1:1000 dilution Lane 1: HL-60 whole cell lysate Lane 2: U937 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

MMP9 Antibody (Cat. AMM02382G) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the MMP9 antibody detected the MMP9 protein (arrow).

Specification

Quantity

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