> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > NUP50 Antibody (ascites)Brand |
Leading Biology | Catalog Number |
AMM02360G |
Product Type |
Monoclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NUP50 Antibody (ascites).
|
||
Molecular Weight |
50144 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis. Associates to the newly formed nuclear membrane during telophase.
|
||
Host |
Mouse
|
||
Species Reactivity |
Human
|
||
Target |
This NUP50 monoclonal antibody is generated from mouse immunized with NUP50 recombinant protein.
|
||
Clone |
247CT10.2.5
|
||
Isotype |
IgG1,k
|
||
Symbol |
NPAP60L
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
|
||
Summary |
The nuclear pore complex is a massive structure thatextends across the nuclear envelope, forming a gateway thatregulates the flow of macromolecules between the nucleus and thecytoplasm. Nucleoporins are the main components of the nuclear porecomplex in eukaryotic cells. The protein encoded by this gene is amember of the FG-repeat containing nucleoporins that functions as asoluble cofactor in importin-alpha:beta-mediated nuclear proteinimport. Pseudogenes of this gene are found on chromosomes 5, 6, and14. Two transcript variants encoding different isoforms have beenfound for this gene.
|
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, E
|
||
Dilution |
WB~~1:1000~3200
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APG02467G | CCK4 / PTK7 Antibody (clone 4F9) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | AMM04683G | GALT Antibody (clone 4C11) | 50 μg | Monoclonal Antibodies |
|
$545.00 | Add Ask | ||
| 3 | Leading Biology | AMM01402G | Vimentin (Mesenchymal Cell Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 4 | Leading Biology | APR08280G | LTA4H / LTA4 Antibody (clone 9G8) | 50 μl | Monoclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | AMM00172G | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide | 50 ug | Monoclonal Antibodies |
|
$395.00 | Add Ask | ||
| 6 | Leading Biology | AMM05750G | CEBPA Antibody | 100 μl | Monoclonal Antibodies |
|
$545.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
