> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > NLRP12 antibody (Ascites)Brand |
Leading Biology | Catalog Number |
AMM02353G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NLRP12 antibody (Ascites).
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Molecular Weight |
120173 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm.
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Host |
Mouse
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Species Reactivity |
Mouse
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Target |
This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
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Clone |
228CT4.1.3
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Isotype |
IgM,K
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Symbol |
NALP12, PYPAF7, RNO
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GeneID |
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UniProt ID |
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Function |
May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
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Summary |
This gene encodes a member of the CATERPILLER family ofcytoplasmic proteins. The encoded protein, which contains anN-terminal pyrin domain, a NACHT domain, a NACHT-associated domain,and a C-terminus leucine-rich repeat region, functions as anattenuating factor of inflammation by suppressing inflammatoryresponses in activated monocytes. Alternatively spliced transcriptvariants encoding distinct isoforms have been described but thefull-length nature of some of these has not been determined.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~1600
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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