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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide

TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM01367G 50 ug / $395

TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide

Brand

Leading Biology

Catalog Number

AMM01367G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide.

Molecular Weight

~6kDa

Cellular Localization

Antigen Cellular Localization: Transforming growth factor alpha: Secreted, extracellular space

Host

Mouse

Species Reactivity

Human

Clone

TGFA/1119

Isotype

Mouse / IgG1, kappa

GeneID

UniProt ID

Function

TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

Summary

This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF? ? (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IF, FC

Images

Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with TGF alpha Monoclonal Antibody (TGFA/1119)

Specification

Quantity

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