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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide

Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide

Catalog # Availability Size / Price Inquiry
AMM00130G 50 ug / $395

Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide

Brand

Leading Biology

Catalog Number

AMM00130G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Lambda Light Chain (B-Cell Marker) Antibody - With BSA and Azide.

Molecular Weight

~22.5kDa

Host

Mouse

Species Reactivity

Human

Target

Purified human IgG

Clone

ICO-106

Isotype

IgG1, kappa

UniProt ID

Summary

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, FC, IP, E

Images

Formalin-paraffin non-Hodgkin's lymphoma stained with Lambda Light Chain Ab (ICO106). Note cell membrane and cytoplasmic staining.

Specification

Quantity

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