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Location: Home > Information Center > Technical FAQs > Antibody Technology Column > What is Antibody Affinity

What is Antibody Affinity

Date: 2020-04-01 Author: Leading Biology Click: 550

Antibody affinity refers to the strength with which the epitope binds to an individual paratope (antigen-binding site) on the antibody. High affinity antibodies bind quickly to the antigen, permit greater sensitivity in assays and maintain this bond more readily under difficult conditions. Low affinity antibodies, by contrast, bind weakly to the antigen and often do not detect the antigen in-vivo or in assays.

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