Introduction

ChIRP, also called Chromatin Isolation by RNA Purification, is a method based on affinity capture of target IncRNA (long non-coding RNA)-Chromatin complex, which then generates a map of genomic binding sites at a resolution of several hundred bases with high sensitivity and low background.

There are many advantages of ChIRP assay, first, it could identify the binding sites anywhere on the genome, second, it enables the discovery of new binding sites, last but not least, it allows the selection of specific RNA. ChIRP is applicable to many IncRNAs because the design of affinity-probes is straightforward given the RNA sequence and requires no knowledge of the RNA’s structure or functional domains.

4. Extracted DNA fraction from ChIRP samples was identified by sequencing or quantitate by qPCR.

Why Leading Biology?

At Leading Biology, we custom protein purification design for every single protein to ensure the production and recovery rate as high as possible.

Working with us, you will get stability, and it means a reliable partner to help streamline your R&D process.

Working with us, you will get the guaranteed service to accommodate your requirements.

· Vigorous quality control system to ensure the required quality and reproducibility

· Competitive price with fast turnaround time

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