ChIP-seq Service_Molecular Biology Services_Custom Services

Introduction

ChIP sequencing is a technique which combines chromatin immunoprecipitation (ChIP) assays and sequencing together, it’s a powerful method for identifying genome-wide DNA binding sites for transcription factors and other proteins.

During ChIP-seq analysis, the proteins are cross-linked to their bound DNA by formaldehyde treatment, cells are homogenized, and chromatin is sheared and immunoprecipitated with antibody-bound magnetic beads. The immunoprecipitated DNA is then used as the input for a next-generation sequencing (NGS) library prep protocol, where it is sequenced and analyzed for DNA binding sites.

ChIP-seq Service

Procedures:
1. Cross-linking: The protein was cross-linked to the chromatin under the effect of formaldehyde.
2. Chromatin fragmentation: Sonication to get the DNA fragment.

3. Immunoprecipitation: collect the wanted DNA.

Why Leading Biology?

At Leading Biology, we custom protein purification design for every single protein to ensure the production and recovery rate as high as possible.

Working with us, you will get stability, and it means a reliable partner to help streamline your R&D process.

Working with us, you will get the guaranteed service to accommodate your requirements.

· Vigorous quality control system to ensure the required quality and reproducibility

· Competitive price with fast turnaround time

Contact Information

Please obtain a quote before ordering, and refer to the quote number when you place an order.

Orders are typically confirmed within 12 hours.

Have a Question? Email us info@leadingbiology.com

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By Phone: 1-661-524(LBI)-0262 (USA)

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