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Location: Home > Information Center > Technical FAQs > Antibody Technology Column > How are Monoclonal Antibodies produced?

How are Monoclonal Antibodies produced?

Date: 2020-04-01 Author: Leading Biology Click: 583


The first monoclonal antibodies (mAbs) have emerged from a survey of hybridomas, and nowadays mAbs are produced mostly from cultivations of these cells. Additionally, there are studies and patents using a range of cells and microorganisms engineered for the production of mAbs at commercial scale. For some years, new methodologies have advanced with new production processes, allowing scale-up production and market introduction. Large-scale production has revolutionized the market for monoclonal antibodies by boosting its production and becoming a more practical method of production. Production techniques have only had a sizable breakthrough due to molecular techniques. Various systems of production are used, including animal cells, microorganisms, plants, and mammary glands. All of these require the technological development of production process such as a stirrer, a wave bioreactor, and roller bottles. Leading Biology mAbs production allows many host species like mouse, rat, rabbit, goat, sheep and chicken. All of the animals are kept in the best health in order to ensure each antibody is manufactured under better conditions.


Leading Biology with over 5 years of experience in custom antibodies service, we offers numerous benefits for developing your custom antibody service.

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