> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00038G-T |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide.
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Molecular Weight |
~6kDa
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Cellular Localization |
Antigen Cellular Localization:
Transforming growth factor alpha: Secreted, extracellular space
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Host |
Mouse
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Species Reactivity |
Human, Zebrafish, Rabbit
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Target |
A 10-amino acid synthetic peptide (aa34-43) from human TGFα.
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Clone |
1E8-G6
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Isotype |
IgG1, kappa
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GeneID |
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UniProt ID |
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Function |
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
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Summary |
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGFα (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, FC, IP, E
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Product Description |
MIC Test Strips are a quantitative assay for determining the Minimum Inhibitory Concentration (MIC) of antimicrobial agents against microorganisms to indicate appropriate patient treatment and for identifying resistance patterns.
Ready to use. No preparation or dilution of antimicrobial agent is required. Simply place on an inoculated agar plate and incubate
MIC testing for a wide range of agents and against many organisms can be done on request and at short notice
Synergy Testing: can be crossed for evaluating a critical assay such as the in vitro combination of antibiotics
Rapid and Efficient: easy to set up. Full range of MIC testing of 6 agents on a large plate takes no more than 5 minutes
Solid Medium: Growth of organisms on agar better mimics in vitro conditions. It is easy to visualize hetero-resistant variants in a population and to detect mixed cultures and contamination
Inoculum Tolerant, Macro.Method: a stable gradient technique that is inoculum tolerant (changes in inoculum do not affect the MIC results for a susceptible strain), thus it can be used in a macro-format with heavier inoculum and a richer media to maximize the detection of low-level and hetero-resistance
Easy to Handle: The package is small and light weigh. Required storage space is minimal
Wide MIC Range: spans across 18 dilutions fulfilling pharmacokinetic needs, varying susceptibility of many organism groups, and covers different MIC breakpoints used in different countries as recommended by various reference or expert groups
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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