> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > Actin, Smooth Muscle (Leiomyosarcoma Marker) Antibody - With BSA and AzideBrand |
Leading Biology | Catalog Number |
AMM00037G-T |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Actin, Smooth Muscle (Leiomyosarcoma Marker) Antibody - With BSA and Azide.
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Molecular Weight |
42kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Mouse
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Species Reactivity |
Human, Mouse, Rat, Guinea Pig
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Target |
N-Terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH
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Clone |
1A4; same as asm-1
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Isotype |
IgG2a, kappa
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Symbol |
ACTSA, ACTVS
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GeneID |
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UniProt ID |
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Function |
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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Summary |
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, IF, FC, IP, E
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Product Description |
MIC Test Strips are a quantitative assay for determining the Minimum Inhibitory Concentration (MIC) of antimicrobial agents against microorganisms to indicate appropriate patient treatment and for identifying resistance patterns.
Ready to use. No preparation or dilution of antimicrobial agent is required. Simply place on an inoculated agar plate and incubate
MIC testing for a wide range of agents and against many organisms can be done on request and at short notice
Synergy Testing: can be crossed for evaluating a critical assay such as the in vitro combination of antibiotics
Rapid and Efficient: easy to set up. Full range of MIC testing of 6 agents on a large plate takes no more than 5 minutes
Solid Medium: Growth of organisms on agar better mimics in vitro conditions. It is easy to visualize hetero-resistant variants in a population and to detect mixed cultures and contamination
Inoculum Tolerant, Macro.Method: a stable gradient technique that is inoculum tolerant (changes in inoculum do not affect the MIC results for a susceptible strain), thus it can be used in a macro-format with heavier inoculum and a richer media to maximize the detection of low-level and hetero-resistance
Easy to Handle: The package is small and light weigh. Required storage space is minimal
Wide MIC Range: spans across 17 dilutions fulfilling pharmacokinetic needs, varying susceptibility of many organism groups, and covers different MIC breakpoints used in different countries as recommended by various reference or expert groups
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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