> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PLCD3 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM07236G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLCD3 antibody (N-term).
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Molecular Weight |
89258 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow. Note=Localizes at the cleavage furrow during cytokinesis
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
60-89 aa
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Target |
This PLCD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PLCD3.
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Isotype |
Rabbit Ig
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Symbol |
KIAA1964
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GeneID |
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UniProt ID |
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Function |
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
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Summary |
This gene encodes a member of the phospholipase C family,which catalyze the hydrolysis of phosphatidylinositol4,5-bisphosphate to generate the second messengers diacylglyceroland inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3mediate a variety of cellular responses to extracellular stimuli byinducing protein kinase C and increasing cytosolic Ca(2+)concentrations. This enzyme localizes to the plasma membrane andrequires calcium for activation. Its activity is inhibited byspermine, sphingosine, and several phospholipids. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, PLCD3, KIAA1964
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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