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RNH1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03694G 100 μl / $495

RNH1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03694G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNH1 Antibody (C-term).

Molecular Weight

49973 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

425-454 aa

Target

This RNH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human RNH1.

Isotype

Rabbit Ig

Symbol

PRI, RNH

GeneID

UniProt ID

Function

Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

Summary

Placental ribonuclease inhibitor (PRI) is a member of afamily of proteinaceous cytoplasmic RNase inhibitors that occur inmany tissues and bind to both intracellular and extracellularRNases (summarized by Lee et al., 1988 [PubMed 3219362]). Inaddition to control of intracellular RNases, the inhibitor may havea role in the regulation of angiogenin (MIM 105850). Ribonucleaseinhibitor, of 50,000 Da, binds to ribonucleases and holds them in alatent form. Since neutral and alkaline ribonucleases probably playa critical role in the turnover of RNA in eukaryotic cells, RNH maybe essential for control of mRNA turnover; the interaction ofeukaryotic cells with ribonuclease may be reversible invivo.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

WB~~1:1000 IF~~1:10~50

Images

Western blot analysis of lysate from HT29 cell line,using RNH1 Antibody (C-term)(Cat. APR03694G).APR03694G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.

Confocal immunofluorescent analysis of RNH1 Antibody (C-term) ( APR03694G) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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