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Anti-alpha-Synuclein Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
AH0002R1 |
Product Type |
Primary Antibody | Field of Research |
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
Recombinant Human alpha-Synuclein protein
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Isotype |
IgG
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Form |
Liquid
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Applications |
WB, ELISA, IHC, IC/IF, IP, FC
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Product Description |
Alpha-synuclein is specifically upregulated in a discrete population of presynaptic terminals of the brain during a period of acquisition-related synaptic rearrangement. It has been shown that alpha-synuclein significantly interacts with tubulin, and that alpha-synuclein may have activity as a potential microtubule-associated protein, like tau. Recent evidence suggests that alpha-synuclein functions as a molecular chaperone in the formation of SNARE complexes. In particular, it simultaneously binds to phospholipids of the plasma membrane via its N-terminus domain and to synaptobrevin-2 via its C-terminus domain, with increased importance during synaptic activity. Indeed, there is growing evidence that alpha-synuclein is involved in the functioning of the neuronal Golgi apparatus and vesicle trafficking. Apparently, alpha-synuclein is essential for normal development of the cognitive functions. Knock-out mice with the targeted inactivation of the expression of alpha-synuclein show impaired spatial learning and working memory.
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Synonyms |
Anti-NACP Antibody; Anti-SNCA Antibody
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Images |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | AMR03742C | Anti-Mu Opioid Receptor antibody - N-terminal | 100ul | Primary Antibody |
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$549.00 | Add Ask | ||
2 | Leading Biology | AMM0008R(Lot#22008R) | Inhibin B (INHB) Antibody | 1 mg | Primary Antibody |
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$975.00 | Add Ask | ||
3 | Leading Biology | AP0296T | Rat Anti-mouse IgG/Gold | 1ml | Primary Antibody |
|
$495.00 | Add Ask | ||
4 | Leading Biology | LM13562T | Purified anti-Podoplanin (Lymphatic Endothelial Marker) Antibody | 100ug | Primary Antibody |
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$495.00 | Add Ask | ||
5 | Leading Biology | AMM0008R(Lot#22009R) | Inhibin B (INHB) Antibody | 1 mg | Primary Antibody |
|
$975.00 | Add Ask | ||
6 | Leading Biology | ARR0003R | Rabbit Anti-Hypusine Recombinant Antibody (clone Hpu24) | 1mg | Primary Antibody |
|
$6950.00 | Add Ask |
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