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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CXCL11 Protein

Recombinant Human CXCL11 Protein

PH0080E2
Catalog # Availability Size / Price Inquiry
PH0080E2-20μg 20μg / $325
PH0080E2-100μg 100μg / $955

Recombinant Human CXCL11 Protein

Brand

Leading Biology

Catalog Number

PH0080E2

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Human

AA Sequence

O14625(Phe22-Phe94)

Tags

Tag-Free

Molecular Weight

9KD

Activity

Measured by its ability to chemoattract human peripheral blood lymphocytes (PBL) cultured in the presence of IL-2 for 21 days.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered 40% acetonitrile, 1% TFA

Product Description

C-X-C motif chemokine 11 (CXCL11) is a protein that in humans is encoded by the CXCL11 gene. C-X-C motif chemokine 11 is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Gene expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. CXCL11 is chemotactic for activated T cells. Its gene is located on human chromosome 4 along with many other members of the CXC chemokine family.

Synonyms

b-R1 Protein(Human); H174 Protein(Human); I-TAC Protein(Human); IP-9 Protein(Human); IP9 Protein(Human); SCYB11 Protein(Human); SCYB9B Protein(Human)

Images

Quantity

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