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CGA Antibody

Catalog # Availability Size / Price Inquiry
APG02562G 100 μl / $545

CGA Antibody

Brand

Leading Biology

Catalog Number

APG02562G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CGA antibody.

Molecular Weight

13075 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Target

A synthetic peptide corresponding to residues at the C terminus of human CGA was used as an immunogen.

Clone

EP3373

GeneID

UniProt ID

Summary

CGA belongs to the glycoprotein hormone alpha chain family that includes the alpha subunit of chronic gonadotropin (CG), lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH). The glycoprotein hormones have the most complex chemical structures of the classical protein hormones. They are dimers consisting of alpha and beta subunits that are associated noncovalently (1, 4). The alpha subunit is common to all of the hormones; however, their beta chains are unique and confer biological specificity (1). These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function (2). The hormones LH, FSH and TSH are secreted by the anterior pituitary gland, while CG is secreted by the placenta (3).

Form

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Dilution

WB~~1:500~1000 IHC~~1:100~250

Synonyms

Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain, CGA

Images

Western blot analysis on JAR cell lysates using anti-CGA RabMAb (Cat. APG02562G). Cells were either (A) treated with Hydroxyurea or (B) untreated.

Immunohistochemical analysis of paraffin-embedded placenta using anti-CGA RabMAb (Cat. APG02562G).

Specification

Quantity

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