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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CCL16 Protein(N-His Tag)

Recombinant Human CCL16 Protein(N-His Tag)

PH0062E3
Catalog # Availability Size / Price Inquiry
PH0062E3-20μg 20μg / $325
PH0062E3-100μg 100μg / $955

Recombinant Human CCL16 Protein(N-His Tag)

Brand

Leading Biology

Catalog Number

PH0062E3

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Human

AA Sequence

NP_004581.1(Gln24-Gln120)

Tags

N-His

Molecular Weight

15KD

Activity

Measured by its ability to chemoattract THP?1 human acute monocytic leukemia cells.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. Its gene is located on chromosome 17, in humans, among a cluster of other CC chemokines. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. C-C motif chemokine ligand 16 has been found in high levels in the blood plasma of humans. CCL16 may be useful for trafficking eosinophils. This ligand has been found to have a functional affinity for H4 receptors that are expressed by eosinophils and mast cells. This chemokine has been shown to suppress rapid proliferation of myeloid progenitor cells.

Synonyms

CKb12 Protein(Human); HCC-4 Protein(Human); ILINCK Protein(Human); LCC-1 Protein(Human); LEC Protein(Human); LMC Protein(Human); Mtn-1 Protein(Human); NCC-4 Protein(Human); NCC4 Protein(Human); SCYA16 Protein(Human); SCYL4 Protein(Human)

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Quantity

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