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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse CCL3 Protein

Recombinant Mouse CCL3 Protein

PM0058E2
Catalog # Availability Size / Price Inquiry
PM0058E2-20μg 20μg / $325
PM0058E2-100μg 100μg / $955

Recombinant Mouse CCL3 Protein

Brand

Leading Biology

Catalog Number

PM0058E2

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

E.coli

Species

Mouse

AA Sequence

P10855(Ala24-Ala92)

Tags

Tag-Free

Molecular Weight

12KD

Activity

Measured by its ability to chemoattract 2-day cultured human monocytes.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered 30% acetonitrile 0.1%TFA

Product Description

CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.through binding to the receptors CCR1, CCR4 and CCR5.CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1. However, in contrast to these two endogenous pyrogens, the fever induced by MIP-1 is not inhibited by the cyclooxygenase inhibitor ibuprofen and CCL3 may participate in the febrile response that is not mediated through prostaglandin synthesis and clinically cannot be ablated by cyclooxygenase.

Synonyms

AI323804 Protein(Mouse); G0S19-1 Protein(Mouse); LD78 alpha Protein(Mouse); MIP-1 alpha Protein(Mouse)

Images

Quantity

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