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Recombinant Mouse ADIPOQ Protein(C-His Tag)Brand |
Leading Biology | Catalog Number |
PM0053M1 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Mouse
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AA Sequence |
NP_033735.3(Met 1-Asn 247)
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Tags |
C-His
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Molecular Weight |
30KD
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Activity |
Measured by its ability to induce TIMP-1 secretion by mouse macrophages.
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Adiponectin is a protein hormone secreted mainly by fat cells, encoded by the ADIPOQ gene and containing 244 amino acids. Adiponectin levels in adults are negatively correlated with fat storage.Adiponectin can bind to several receptors, and the two receptors share homology with G protein-coupled receptors, one belonging to the cadherin family.These have distinct tissue specificities within the body and have different affinities to the various forms of adiponectin. The receptors affect the downstream target AMP kinase, an important cellular metabolic rate control point. Expression of the receptors is correlated with insulin levels, as well as reduced in mouse models of diabetes, particularly in skeletal muscle and adipose tissue.
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Synonyms |
Acdc Protein(Mouse); Acrp30 Protein(Mouse); Ad Protein(Mouse); adipo Protein(Mouse); apM1 Protein(Mouse); APN Protein(Mouse); GBP28 Protein(Mouse)
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Images |
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Quantity |
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